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KMID : 0616120160470020110
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Korean Journal of Pharmacognosy
2016 Volume.47 No. 2 p.110 ~ p.116
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Antioxidant Components of the Aerial Parts of Bidens frondosa L.
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Ahn Dal-Rae
Kim Dae-Keun
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Abstract
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As a part of an ongoing search for natural plants with antioxidant compounds by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH), a total extract of the aerial parts of Bidens frondosa L. (Compositae) was found to show potent antioxidant activity. Subsequent activity-guided fractionation of the methanolic extract led to the isolation of five compounds, quercetin-3-O-b-D-glucopyranoside (1), luteolin-7-O-b-D-glucopyranoside (2), 7,8,3',4'-tertrahydroxyflavanone (3), okanin-4-O-b-D-glucopyranoside (4), and okanin (5). Their structures were elucidated by spectroscopic studies. Compounds 3-5 were isolated for the first time from this plant. Among them, compounds 3 and 5 showed the significant radical scavenging effects on DPPH, and compounds 3 and 5 also showed the potent riboflavin and xanthine originated superoxide quenching activities.
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KEYWORD
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Bidens frondosa L. , Compositae , Antioxidant activity , DPPH radical , Superoxide quenching activity
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